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Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities

[Image: see text] SARS-CoV-2 infection is still spreading worldwide, and new antiviral therapies are an urgent need to complement the approved vaccine preparations. SARS-CoV-2 nps13 helicase is a validated drug target participating in the viral replication complex and possessing two associated activ...

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Detalles Bibliográficos
Autores principales: Corona, Angela, Wycisk, Krzysztof, Talarico, Carmine, Manelfi, Candida, Milia, Jessica, Cannalire, Rolando, Esposito, Francesca, Gribbon, Philip, Zaliani, Andrea, Iaconis, Daniela, Beccari, Andrea R., Summa, Vincenzo, Nowotny, Marcin, Tramontano, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003574/
https://www.ncbi.nlm.nih.gov/pubmed/35434533
http://dx.doi.org/10.1021/acsptsci.1c00253