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Inclusive Trial Designs in Acute Spinal Cord Injuries: Prediction–Based Stratification of Clinical Walking Outcome and Projected Enrolment Frequencies

BACKGROUND: New therapeutic approaches in neurological disorders are progressing into clinical development. Past failures in translational research have underlined the critical importance of selecting appropriate inclusion criteria and primary outcomes. Narrow inclusion criteria provide sensitivity,...

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Detalles Bibliográficos
Autores principales: Cathomen, Adrian, Sirucek, Laura, Killeen, Tim, Abel, Rainer, Maier, Doris, Weidner, Norbert, Rupp, Rüdiger, Hothorn, Torsten, Steeves, John D., Curt, Armin, Bolliger, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003761/
https://www.ncbi.nlm.nih.gov/pubmed/35164574
http://dx.doi.org/10.1177/15459683221078302