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Inclusive Trial Designs in Acute Spinal Cord Injuries: Prediction–Based Stratification of Clinical Walking Outcome and Projected Enrolment Frequencies
BACKGROUND: New therapeutic approaches in neurological disorders are progressing into clinical development. Past failures in translational research have underlined the critical importance of selecting appropriate inclusion criteria and primary outcomes. Narrow inclusion criteria provide sensitivity,...
Autores principales: | Cathomen, Adrian, Sirucek, Laura, Killeen, Tim, Abel, Rainer, Maier, Doris, Weidner, Norbert, Rupp, Rüdiger, Hothorn, Torsten, Steeves, John D., Curt, Armin, Bolliger, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003761/ https://www.ncbi.nlm.nih.gov/pubmed/35164574 http://dx.doi.org/10.1177/15459683221078302 |
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