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Uncarboxylated osteocalcin promotes proliferation and metastasis of MDA-MB-231 cells through TGF-β/SMAD3 signaling pathway

BACKGROUND: Triple-negative breast cancer (TNBC) is the most severe type of breast cancer owing to its high heterogeneity, aggressiveness and lack of treatment. Studies have reported that uncarboxylated osteocalcin (GluOC) promotes the development of prostate and other cancers. Studies have also fou...

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Detalles Bibliográficos
Autores principales: Xu, Jiaojiao, Ma, Luyao, Wang, Danqing, Yang, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003967/
https://www.ncbi.nlm.nih.gov/pubmed/35413833
http://dx.doi.org/10.1186/s12860-022-00416-7