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Increased expression of TIGIT and KLRG1 correlates with impaired CD56(bright) NK cell immunity in HPV16-related cervical intraepithelial neoplasia

BACKGROUND: The onset and progression of cervical intraepithelial neoplasia (CIN) are closely associated with the persistent infection of high-risk HPV (especially type16), which is mainly caused by immune escape. Natural killer (NK) cells play an important role against virally infected cells and tu...

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Detalles Bibliográficos
Autores principales: Nie, You, Liu, Dandan, Yang, Wen, Li, Yazhuo, Zhang, Lihua, Cheng, Xia, Chen, Ruyu, Yuan, Bingbing, Zhang, Guangzheng, Wang, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003970/
https://www.ncbi.nlm.nih.gov/pubmed/35413989
http://dx.doi.org/10.1186/s12985-022-01776-4