Evaluation of a 4-day repeated-dose micronucleus test in rat glandular stomach and colon using aneugens and non-genotoxic non-carcinogens

BACKGROUND: We previously developed a rodent gastrointestinal (GI) tract micronucleus (MN) test using the glandular stomach and/or colon, and evaluated this test method using several genotoxic carcinogens (clastogens) and genotoxic non-carcinogens; we demonstrated that this test method could detect...

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Detalles Bibliográficos
Autores principales: Okada, Emiko, Fujiishi, Yohei, Narumi, Kazunori, Ohyama, Wakako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004010/
https://www.ncbi.nlm.nih.gov/pubmed/35410395
http://dx.doi.org/10.1186/s41021-022-00241-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004010/
https://www.ncbi.nlm.nih.gov/pubmed/35410395
http://dx.doi.org/10.1186/s41021-022-00241-6

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