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Evaluation of a 4-day repeated-dose micronucleus test in rat glandular stomach and colon using aneugens and non-genotoxic non-carcinogens
BACKGROUND: We previously developed a rodent gastrointestinal (GI) tract micronucleus (MN) test using the glandular stomach and/or colon, and evaluated this test method using several genotoxic carcinogens (clastogens) and genotoxic non-carcinogens; we demonstrated that this test method could detect...
Autores principales: | Okada, Emiko, Fujiishi, Yohei, Narumi, Kazunori, Ohyama, Wakako |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004010/ https://www.ncbi.nlm.nih.gov/pubmed/35410395 http://dx.doi.org/10.1186/s41021-022-00241-6 |
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