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Single-cell analysis of p53 transitional dynamics unravels stimulus- and cell type-dependent signaling output motifs
BACKGROUND: To understand functional changes of complex biological networks, mathematical modeling of network topologies provides a quantitative measure of the way biological systems adapt to external stimuli. However, systemic network topology-based analysis often generates conflicting evidence dep...
Autores principales: | Xie, Jun, Zhang, Lichun, Liu, Bodong, Liang, Xiao, Shi, Jue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004066/ https://www.ncbi.nlm.nih.gov/pubmed/35410287 http://dx.doi.org/10.1186/s12915-022-01290-7 |
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