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Notch1 activation of Jagged1 contributes to differentiation of mesenchymal stem cells into endothelial cells under cigarette smoke extract exposure

BACKGROUND: Mesenchymal stem cells (MSCs) have shown therapeutic potential for engraftment to, differentiation into, endothelial cells (ECs). However, low-efficiency yields hinder their use as ECs for therapeutic vascularization. METHODS: The Notch1 signaling pathway is key to optimal pulmonary deve...

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Detalles Bibliográficos
Autores principales: Cheng, Yi, Gu, Wen, Zhang, Guorui, Guo, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004089/
https://www.ncbi.nlm.nih.gov/pubmed/35410206
http://dx.doi.org/10.1186/s12890-022-01913-3