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Notch1 activation of Jagged1 contributes to differentiation of mesenchymal stem cells into endothelial cells under cigarette smoke extract exposure
BACKGROUND: Mesenchymal stem cells (MSCs) have shown therapeutic potential for engraftment to, differentiation into, endothelial cells (ECs). However, low-efficiency yields hinder their use as ECs for therapeutic vascularization. METHODS: The Notch1 signaling pathway is key to optimal pulmonary deve...
Autores principales: | Cheng, Yi, Gu, Wen, Zhang, Guorui, Guo, Xuejun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004089/ https://www.ncbi.nlm.nih.gov/pubmed/35410206 http://dx.doi.org/10.1186/s12890-022-01913-3 |
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