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Identification of Aloe-derived natural products as prospective lead scaffolds for SARS-CoV-2 main protease (M(pro)) inhibitors

In the past two years, the COVID-19 pandemic has caused over 5 million deaths and 250 million infections worldwide. Despite successful vaccination efforts and emergency approval of small molecule therapies, a diverse range of antivirals is still needed to combat the inevitable resistance that will a...

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Detalles Bibliográficos
Autores principales: Hicks, Emily G., Kandel, Sylvie E., Lampe, Jed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004148/
https://www.ncbi.nlm.nih.gov/pubmed/35427739
http://dx.doi.org/10.1016/j.bmcl.2022.128732