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Canalization of the Polygenic Risk for Common Diseases and Traits in the UK Biobank Cohort
Since organisms develop and thrive in the face of constant perturbations due to environmental and genetic variation, species may evolve resilient genetic architectures. We sought evidence for this process, known as canalization, through a comparison of the prevalence of phenotypes as a function of t...
Autores principales: | Nagpal, Sini, Tandon, Raghav, Gibson, Greg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004416/ https://www.ncbi.nlm.nih.gov/pubmed/35275999 http://dx.doi.org/10.1093/molbev/msac053 |
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