The Structural Determinants of Intra-Protein Compensatory Substitutions

Compensatory substitutions happen when one mutation is advantageously selected because it restores the loss of fitness induced by a previous deleterious mutation. How frequent such mutations occur in evolution and what is the structural and functional context permitting their emergence remain open q...

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Detalles Bibliográficos
Autores principales: Chaurasia, Shilpi, Dutheil, Julien Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004419/
https://www.ncbi.nlm.nih.gov/pubmed/35349721
http://dx.doi.org/10.1093/molbev/msac063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004419/
https://www.ncbi.nlm.nih.gov/pubmed/35349721
http://dx.doi.org/10.1093/molbev/msac063

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