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The Structural Determinants of Intra-Protein Compensatory Substitutions
Compensatory substitutions happen when one mutation is advantageously selected because it restores the loss of fitness induced by a previous deleterious mutation. How frequent such mutations occur in evolution and what is the structural and functional context permitting their emergence remain open q...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004419/ https://www.ncbi.nlm.nih.gov/pubmed/35349721 http://dx.doi.org/10.1093/molbev/msac063 |