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Both Natural and Induced Anti-Sda Antibodies Play Important Roles in GTKO Pig-to-Rhesus Monkey Xenotransplantation

Sda, produced by the B4GALNT2 enzyme, has been recognized as an important xenoantigen for pig-to-nonhuman primate xenotransplantation. However, little is known about Sda expression in pigs and its immunogenicity in xenotransplantation. In this study, peripheral blood mononuclear cells (PBMCs) were i...

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Detalles Bibliográficos
Autores principales: Feng, Hao, Li, Tao, Du, Jiaxiang, Xia, Qiangbing, Wang, Lu, Chen, Song, Zhu, Lan, Pan, Dengke, Wang, Yi, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004458/
https://www.ncbi.nlm.nih.gov/pubmed/35422817
http://dx.doi.org/10.3389/fimmu.2022.849711