Cargando…

Iguratimod alleviates tubulo-interstitial injury in mice with lupus

INTRODUCTION: Tubulo-interstitial injury is a poor prognostic factor for lupus nephritis (LN). Here, we tested whether iguratimod could inhibit tubulo-interstitial injury in LN. METHODS: MRL/lpr mice, an animal model of lupus, were treated with iguratimod or vehicle solution. Pathological changes of...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Leixi, Xu, Jiajun, Lu, Wentian, Fu, Jinxiang, Liu, Zhichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004506/
https://www.ncbi.nlm.nih.gov/pubmed/35387545
http://dx.doi.org/10.1080/0886022X.2022.2058962