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Glomerular endothelial expression of type I IFN-stimulated gene, DExD/H-Box helicase 60 via toll-like receptor 3 signaling: possible involvement in the pathogenesis of lupus nephritis

BACKGROUND: Sustained type I interferon (IFN) activation via Toll-like receptor (TLR) 3, 7 and 9 signaling has been reported to play a pivotal role in the development of lupus nephritis (LN). Although type I IFN activation has been shown to induce interferon-stimulated genes (ISGs) expression in sys...

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Detalles Bibliográficos
Autores principales: Karasawa, Takao, Sato, Riko, Imaizumi, Tadaatsu, Hashimoto, Shun, Fujita, Masashi, Aizawa, Tomomi, Tsugawa, Koji, Kawaguchi, Shogo, Seya, Kazuhiko, Terui, Kiminori, Tanaka, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004514/
https://www.ncbi.nlm.nih.gov/pubmed/35392757
http://dx.doi.org/10.1080/0886022X.2022.2027249