Microbubble drug conjugate and focused ultrasound blood brain barrier delivery of AAV-2 SIRT-3

BACKGROUND: Delivery of viral vectors as gene therapies to treat neurodegenerative diseases has been hampered by the inability to penetrate the blood brain barrier (BBB) and invasive or non-targeted delivery options prone to inducing immune responses. MR guided focused ultrasound (MR-g-FUS) and micr...

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Detalles Bibliográficos
Autores principales: Trinh, Dennison, Nash, Joanne, Goertz, David, Hynynen, Kullervo, Bulner, Sharsi, Iqbal, Umar, Keenan, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004516/
https://www.ncbi.nlm.nih.gov/pubmed/35393905
http://dx.doi.org/10.1080/10717544.2022.2035855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004516/
https://www.ncbi.nlm.nih.gov/pubmed/35393905
http://dx.doi.org/10.1080/10717544.2022.2035855

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