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Fast and accurate gene regulatory network inference by normalized least squares regression

MOTIVATION: Inferring an accurate gene regulatory network (GRN) has long been a key goal in the field of systems biology. To do this, it is important to find a suitable balance between the maximum number of true positive and the minimum number of false-positive interactions. Another key feature is t...

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Detalles Bibliográficos
Autores principales: Hillerton, Thomas, Seçilmiş, Deniz, Nelander, Sven, Sonnhammer, Erik L L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004640/
https://www.ncbi.nlm.nih.gov/pubmed/35176145
http://dx.doi.org/10.1093/bioinformatics/btac103