A kinetic fluorescence polarization ligand assay for monitoring BAX early activation

Developmental, homeostatic, and pharmacological pro-apoptotic signals converge by activating the BCL-2 family member BAX. Studies investigating molecular regulation of BAX are commonly limited to methodologies measuring endpoint phenotypes and do not assess activation of monomeric BAX. Here, we pres...

Descripción completa

Detalles Bibliográficos
Autores principales: Gelles, Jesse D., Mohammed, Jarvier N., Chen, Yiyang, Sebastian, Tara M., Chipuk, Jerry Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004659/
https://www.ncbi.nlm.nih.gov/pubmed/35419554
http://dx.doi.org/10.1016/j.crmeth.2022.100174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004659/
https://www.ncbi.nlm.nih.gov/pubmed/35419554
http://dx.doi.org/10.1016/j.crmeth.2022.100174

Ejemplares similares