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A kinetic fluorescence polarization ligand assay for monitoring BAX early activation

Developmental, homeostatic, and pharmacological pro-apoptotic signals converge by activating the BCL-2 family member BAX. Studies investigating molecular regulation of BAX are commonly limited to methodologies measuring endpoint phenotypes and do not assess activation of monomeric BAX. Here, we pres...

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Detalles Bibliográficos
Autores principales:	Gelles, Jesse D., Mohammed, Jarvier N., Chen, Yiyang, Sebastian, Tara M., Chipuk, Jerry Edward
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004659/ https://www.ncbi.nlm.nih.gov/pubmed/35419554 http://dx.doi.org/10.1016/j.crmeth.2022.100174

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