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MD Simulations Revealing Special Activation Mechanism of Cannabinoid Receptor 1
Cannabinoid receptor 1 (CB1) is a G protein-coupled receptor (GPCR) that is gaining much interest for its regulating role in the central nervous system and its value as a drug target. Structures of CB1 in inactive and active states have revealed conformational change details that are not common in o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004671/ https://www.ncbi.nlm.nih.gov/pubmed/35425811 http://dx.doi.org/10.3389/fmolb.2022.860035 |