Ataxia telangiectasia and Rad3-related inhibition by AZD6738 enhances gemcitabine-induced cytotoxic effects in bladder cancer cells

The ataxia telangiectasia and rad3-related-checkpoint kinase 1 (ATR-CHK1) pathway is involved in DNA damage responses in many cancer cells. ATR inhibitors have been used in clinical trials in combination with radiation or chemotherapeutics; however, their effects against bladder cancer remain unclea...

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Detalles Bibliográficos
Autores principales: Isono, Makoto, Okubo, Kazuki, Asano, Takako, Sato, Akinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004738/
https://www.ncbi.nlm.nih.gov/pubmed/35413091
http://dx.doi.org/10.1371/journal.pone.0266476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004738/
https://www.ncbi.nlm.nih.gov/pubmed/35413091
http://dx.doi.org/10.1371/journal.pone.0266476

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