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KLF11 deficiency enhances chemokine generation and fibrosis in murine unilateral ureteral obstruction

Progression of virtually all forms of chronic kidney disease (CKD) is associated with activation of pro-inflammatory and pro-fibrotic signaling pathways. Despite extensive research, progress in identifying therapeutic targets to arrest or slow progression of CKD has been limited by incomplete unders...

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Detalles Bibliográficos
Autores principales: De Lorenzo, Silvana B., Vrieze, Alyssa M., Johnson, Ruth A., Lien, Karen R., Nath, Karl A., Garovic, Vesna D., Khazaie, Khashayarsha, Grande, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004740/
https://www.ncbi.nlm.nih.gov/pubmed/35413089
http://dx.doi.org/10.1371/journal.pone.0266454