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Unraveling the molecular determinants of the anti-phagocytic protein cloak of plague bacteria

The pathogenic bacterium Yersina pestis is protected from macrophage engulfment by a capsule like antigen, F1, formed of long polymers of the monomer protein, Caf1. However, despite the importance of this pathogen, the mechanism of protection was not understood. Here we demonstrate how F1 protects t...

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Detalles Bibliográficos
Autores principales: Peters, Daniel T., Reifs, Antonio, Alonso-Caballero, Alvaro, Madkour, Azzeldin, Waller, Helen, Kenny, Brendan, Perez-Jimenez, Raul, Lakey, Jeremy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004762/
https://www.ncbi.nlm.nih.gov/pubmed/35358289
http://dx.doi.org/10.1371/journal.ppat.1010447