Common coupling map advances GPCR-G protein selectivity

Two-thirds of human hormones and one-third of clinical drugs act on membrane receptors that couple to G proteins to achieve appropriate functional responses. While G protein transducers from literature are annotated in the Guide to Pharmacology database, two recent large-scale datasets now expand th...

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Detalles Bibliográficos
Autores principales: Hauser, Alexander S, Avet, Charlotte, Normand, Claire, Mancini, Arturo, Inoue, Asuka, Bouvier, Michel, Gloriam, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005189/
https://www.ncbi.nlm.nih.gov/pubmed/35302494
http://dx.doi.org/10.7554/eLife.74107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005189/
https://www.ncbi.nlm.nih.gov/pubmed/35302494
http://dx.doi.org/10.7554/eLife.74107

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