The effect of BI 409306 on heart rate in healthy volunteers: a randomised, double-blind, placebo-controlled, crossover study

PURPOSE: The potent, selective phosphodiesterase-9A inhibitor BI 409306 may be beneficial for patients with attenuated psychosis syndrome and could prevent relapse in patients with schizophrenia. Transient BI 409306-dependent increases in heart rate (HR) demonstrated previously necessitated cardiac...

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Detalles Bibliográficos
Autores principales: Müller, Fabian, Sand, Michael, Wunderlich, Glen, Link, Jasmin, Schultheis, Christian, Dansirikul, Chantaratsamon, Sane, Rucha, Laszlo, Roman, Steinacker, Jürgen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005427/
https://www.ncbi.nlm.nih.gov/pubmed/35089373
http://dx.doi.org/10.1007/s00228-022-03274-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005427/
https://www.ncbi.nlm.nih.gov/pubmed/35089373
http://dx.doi.org/10.1007/s00228-022-03274-6

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