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OCT1-target neural gene PFN2 promotes tumor growth in androgen receptor-negative prostate cancer

Androgen and androgen receptor (AR) targeted therapies are the main treatment for most prostate cancer (PC) patients. Although AR signaling inhibitors are effective, tumors can evade this treatment by transforming to an AR-negative PC via lineage plasticity. OCT1 is a transcription factor interactin...

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Detalles Bibliográficos
Autores principales: Obinata, Daisuke, Funakoshi, Daigo, Takayama, Kenichi, Hara, Makoto, Niranjan, Birunthi, Teng, Linda, Lawrence, Mitchell G., Taylor, Renea A., Risbridger, Gail P., Suzuki, Yutaka, Takahashi, Satoru, Inoue, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005514/
https://www.ncbi.nlm.nih.gov/pubmed/35413990
http://dx.doi.org/10.1038/s41598-022-10099-x