Cargando…

A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression

As a key regulator of the DNA translesion synthesis (TLS) pathway, RAD18 is error-prone and contributes to the accumulation of DNA mutations. Our previous study showed that it plays an essential role in the progression of multiple tumors. However, the mechanism through which RAD18 influences triple-...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Xueqi, He, Yaozhou, Yang, Shikun, Zeng, Tianyu, Hua, Yijia, Bao, Shengnan, Yang, Fan, Duan, Ningjun, Sun, Chunxiao, Liang, Yan, Fu, Ziyi, Huang, Xiang, Li, Wei, Yin, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005530/
https://www.ncbi.nlm.nih.gov/pubmed/35413945
http://dx.doi.org/10.1038/s41420-022-00968-9