Cargando…

A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression

As a key regulator of the DNA translesion synthesis (TLS) pathway, RAD18 is error-prone and contributes to the accumulation of DNA mutations. Our previous study showed that it plays an essential role in the progression of multiple tumors. However, the mechanism through which RAD18 influences triple-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Xueqi, He, Yaozhou, Yang, Shikun, Zeng, Tianyu, Hua, Yijia, Bao, Shengnan, Yang, Fan, Duan, Ningjun, Sun, Chunxiao, Liang, Yan, Fu, Ziyi, Huang, Xiang, Li, Wei, Yin, Yongmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005530/ https://www.ncbi.nlm.nih.gov/pubmed/35413945 http://dx.doi.org/10.1038/s41420-022-00968-9

Ejemplares similares

Exosome-Transmitted tRF-16-K8J7K1B Promotes Tamoxifen Resistance by Reducing Drug-Induced Cell Apoptosis in Breast Cancer
por: Sun, Chunxiao, et al.
Publicado: (2023)

A Real-World Multicentre Retrospective Study of Low-Dose Apatinib for Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer
por: Zeng, Tianyu, et al.
Publicado: (2022)

Safety profile of poly (ADP-ribose) polymerase (PARP) inhibitors in cancer: a network meta-analysis of randomized controlled trials
por: Bao, Shengnan, et al.
Publicado: (2021)

Comprehensive description of the current breast cancer microenvironment advancements via single-cell analysis
por: Yan, Xueqi, et al.
Publicado: (2021)

Nonmetastatic breast cancer patients subsequently developing second primary malignancy: A population‐based study
por: Bao, Shengnan, et al.
Publicado: (2021)

LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma
por: Liao, Jianping, et al.
Publicado: (2023)

Identification of a novel YAP–14-3-3ζ negative feedback loop in gastric cancer
por: Zhang, Bin, et al.
Publicado: (2017)

A Feedback Loop Regulation Of LINC01433 And YAP Promotes Malignant Behavior In Gastric Cancer Cells
por: Zhang, Cao, et al.
Publicado: (2019)

A SMYD3/ITGB6/TGFβ1 Positive Feedback Loop Promotes the Invasion and Adhesion of Ovarian Cancer Spheroids
por: Jiang, Yahui, et al.
Publicado: (2021)

Negative feedback loop between ZBTB7A and TGF-β in breast cancer
por: Shen, Yingying, et al.
Publicado: (2017)

Risk Signature of Cancer-Associated Fibroblast–Secreted Cytokines Associates With Clinical Outcomes of Breast Cancer
por: Sun, Chunxiao, et al.
Publicado: (2021)

High rate of epidermal growth factor receptor-mutated primary lung cancer in patients with primary breast cancer
por: Zeng, Tianyu, et al.
Publicado: (2022)

A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis
por: Shen, Shuying, et al.
Publicado: (2015)

A Negative Feedback Loop Between NAMPT and TGF-β Signaling Pathway in Colorectal Cancer Cells
por: Lv, Xiaoqun, et al.
Publicado: (2021)

The feedback loop of ANKHD1/lncRNA MALAT1/YAP1 strengthens the radioresistance of CRC by activating YAP1/AKT signaling
por: Yao, Ping-an, et al.
Publicado: (2022)

High mobility group box 1 regulates gastric cancer cell proliferation and migration via RAGE-mTOR/ERK feedback loop
por: Tang, Tuo, et al.
Publicado: (2021)

SNHG16 upregulation-induced positive feedback loop with YAP1/TEAD1 complex in Colorectal Cancer cell lines facilitates liver metastasis of colorectal cancer by modulating CTCs epithelial-mesenchymal transition
por: Xiang, Zhenxian, et al.
Publicado: (2022)

The Role of Feedback Loops in Targeted Therapy for Pancreatic Cancer
por: Gu, Weigang, et al.
Publicado: (2022)

Long non-coding RNA SNHG1 activates HOXA1 expression via sponging miR-193a-5p in breast cancer progression
por: Li, Jun, et al.
Publicado: (2020)

Influence of the Hippo-YAP signalling pathway on tumor associated macrophages (TAMs) and its implications on cancer immunosuppressive microenvironment
por: Yang, Wenjie, et al.
Publicado: (2020)

RAD18 promotes colorectal cancer metastasis by activating the epithelial-mesenchymal transition pathway
por: Li, Peng, et al.
Publicado: (2020)

miR-340 and ZEB1 negative feedback loop regulates TGF-β- mediated breast cancer progression
por: Hou, Li-Kun, et al.
Publicado: (2016)

A Positive TGF-β/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer()()
por: Rojas, Andres, et al.
Publicado: (2016)

An epigenetic auto-feedback loop regulates TGF-β type II receptor expression and function in NSCLC
por: Yang, Shanzhong, et al.
Publicado: (2015)

Autophagy-mediated negative feedback attenuates the oncogenic activity of YAP in pancreatic cancer
por: Sun, Ting, et al.
Publicado: (2021)

The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin
por: Wang, Zehao, et al.
Publicado: (2022)

Reciprocal Feedback Loop of the MALAT1-MicroRNA-194-YAP1 Pathway Regulates Progression of Acute Pancreatitis
por: Gu, Lina, et al.
Publicado: (2019)

miR-1269 Promotes Metastasis and Forms a Positive Feedback Loop with TGF-β
por: Bu, Pengcheng, et al.
Publicado: (2015)

A Positive Feedback Loop of TET3 and TGF-β1 Promotes Liver Fibrosis
por: Xu, Yetao, et al.
Publicado: (2020)

RAD51AP1 promotes progression of ovarian cancer via TGF‐β/Smad signalling pathway
por: Zhao, Hongyu, et al.
Publicado: (2020)

Piezo1 activation facilitates ovarian cancer metastasis via Hippo/YAP signaling axis
por: Xiong, Yanjie, et al.
Publicado: (2022)

Activation of TGF-β1-CD147 positive feedback loop in hepatic stellate cells promotes liver fibrosis
por: Li, Hai-Yan, et al.
Publicado: (2015)

Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer
por: Gao, Chao, et al.
Publicado: (2021)

YAP forms autocrine loops with the ERBB pathway to regulate ovarian cancer initiation and progression
por: He, Chunbo, et al.
Publicado: (2015)

The TGF(β)→TAK1→LATS→YAP1 Pathway Regulates the Spatiotemporal Dynamics of YAP1
por: Kim, Min-Kyu, et al.
Publicado: (2023)

TGFβ promotes YAP‐dependent AXL induction in mesenchymal‐type lung cancer cells
por: Choi, Jeong‐Yun, et al.
Publicado: (2020)

RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axis
por: Li, Zhongbo, et al.
Publicado: (2022)

SRGN-TGFβ2 regulatory loop confers invasion and metastasis in triple-negative breast cancer
por: Zhang, Z, et al.
Publicado: (2017)

A negative feedback loop between JNK-associated leucine zipper protein and TGF-β1 regulates kidney fibrosis
por: Yan, Qi, et al.
Publicado: (2020)

EDIL3 regulates gastric cancer cell migration, invasion and epithelial-mesenchymal transition via TGF-β1/XIST/miR-137 feedback loop
por: Zhang, Li, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4o2qoqv2aesgjtmpgb32gvnq1k