Cargando…

PET imaging of mitochondrial function in acute doxorubicin-induced cardiotoxicity: a proof-of-principle study

Mitochondrial dysfunction plays a key role in doxorubicin-induced cardiotoxicity (DIC). In this proof-of-principle study, we investigated whether PET mapping of cardiac membrane potential, an indicator of mitochondrial function, could detect an acute cardiotoxic effect of doxorubicin (DOX) in a larg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Detmer, Felicitas J., Alpert, Nathaniel M., Moon, Sung-Hyun, Dhaynaut, Maeva, Guerrero, J. Luis, Guehl, Nicolas J., Xing, Fangxu, Brugarolas, Pedro, Shoup, Timothy M., Normandin, Marc D., Pelletier-Galarneau, Matthieu, El Fakhri, Georges, Petibon, Yoann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005533/ https://www.ncbi.nlm.nih.gov/pubmed/35414642 http://dx.doi.org/10.1038/s41598-022-10004-6

Ejemplares similares

In-vivo Imaging of Mitochondrial Depolarization of Myocardium With Positron Emission Tomography and a Proton Gradient Uncoupler
por: Alpert, Nathaniel M., et al.
Publicado: (2020)

Radiochemical Synthesis and Evaluation of 3-[(11)C]Methyl-4-aminopyridine in Rodents and Nonhuman Primates for Imaging Potassium Channels in the CNS
por: Sun, Yang, et al.
Publicado: (2022)

Quantitative in vivo mapping of myocardial mitochondrial membrane potential
por: Alpert, Nathaniel M., et al.
Publicado: (2018)

PET imaging of neurotransmission using direct parametric reconstruction
por: Petibon, Yoann, et al.
Publicado: (2020)

Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue
por: Aguero, Cinthya, et al.
Publicado: (2019)

Evaluation of trans- and cis-4-[(18)F]fluorogabapentin for brain PET imaging
por: Zhou, Yu-Peng, et al.
Publicado: (2023)

Super-resolution in brain positron emission tomography using a real-time motion capture system
por: Chemli, Yanis, et al.
Publicado: (2023)

In vivo imaging of mGlu5 receptor expression in humans with Fragile X Syndrome towards development of a potential biomarker
por: Mody, Maria, et al.
Publicado: (2021)

INKing the Cardiotoxicity Out of Doxorubicin
por: Guo, Zhen, et al.
Publicado: (2023)

Tau Positron Emission Tomography and Neurocognitive Function Among Former Professional American-Style Football Players
por: Dhaynaut, Maeva, et al.
Publicado: (2023)

Role of acetylation in doxorubicin-induced cardiotoxicity
por: Li, Daisong, et al.
Publicado: (2021)

Dipyridamole ameliorates doxorubicin-induced cardiotoxicity
por: Alyasiry, Esraa, et al.
Publicado: (2022)

MR-based motion correction for cardiac PET parametric imaging: a simulation study
por: Guo, Rong, et al.
Publicado: (2018)

Doxorubicin-Induced Cardiotoxicity in Collaborative Cross (CC) Mice Recapitulates Individual Cardiotoxicity in Humans
por: Zeiss, Caroline J., et al.
Publicado: (2019)

The Role of AMPK Activation for Cardioprotection in Doxorubicin-Induced Cardiotoxicity
por: Timm, Kerstin N., et al.
Publicado: (2020)

Morphine Enhances Doxorubicin-Induced Cardiotoxicity in the Rat
por: Hole, Lisa Drange, et al.
Publicado: (2014)

The true colors of autophagy in doxorubicin-induced cardiotoxicity
por: Xiao, Bin, et al.
Publicado: (2019)

UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity
por: An, Lin, et al.
Publicado: (2017)

Autophagy and mitophagy in the context of doxorubicin-induced cardiotoxicity
por: Koleini, Navid, et al.
Publicado: (2017)

Telomerase therapy attenuates cardiotoxic effects of doxorubicin
por: Chatterjee, Shambhabi, et al.
Publicado: (2021)

Combat Doxorubicin Cardiotoxicity With the Power of Mitochondria Transfer
por: Wang, Dennis D., et al.
Publicado: (2021)

Mitochondrial-Targeted Therapy for Doxorubicin-Induced Cardiotoxicity
por: Wu, Bin Bin, et al.
Publicado: (2022)

Can ARNI Prevent Doxorubicin-Induced Cardiotoxicity?
por: Özgür Barış, Veysel, et al.
Publicado: (2022)

Protection against Doxorubicin-Induced Cardiotoxicity by Ergothioneine
por: Cheah, Irwin K., et al.
Publicado: (2023)

Hyperhomocysteinaemia Promotes Doxorubicin-Induced Cardiotoxicity in Mice
por: Fan, Rui, et al.
Publicado: (2023)

Bibliometric and visual analysis of doxorubicin-induced cardiotoxicity
por: Lin, Xiaoxiao, et al.
Publicado: (2023)

The Essential Strategies to Mitigate Cardiotoxicity Caused by Doxorubicin
por: Chaulin, Aleksey Michailovich
Publicado: (2023)

Effects of Calorie Restriction and Voluntary Exercise on Doxorubicin-Induced Cardiotoxicity
por: Hall, Stephanie E., et al.
Publicado: (2019)

Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27
por: Bernard, Yohann, et al.
Publicado: (2011)

Doxorubicin-induced cardiotoxicity in adult Indian patients on chemotherapy
por: Khattry, Navin, et al.
Publicado: (2009)

Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat
por: Hole, Lisa Drange, et al.
Publicado: (2014)

A Novel Insight into the Cardiotoxicity of Antineoplastic Drug Doxorubicin
por: Heger, Zbynek, et al.
Publicado: (2013)

Protective effect of silymarin on doxorubicin-induced cardiotoxicity in rats
por: Stilinović, Nebojša, et al.
Publicado: (2012)

Nebivolol effect on doxorubicin-induced cardiotoxicity in breast cancer
por: Cochera, Flavia, et al.
Publicado: (2018)

Low dose radiation prevents doxorubicin-induced cardiotoxicity
por: Jiang, Xin, et al.
Publicado: (2017)

Protective effect of nebivolol on doxorubicin-induced cardiotoxicity in rats
por: Mohamed, Enas Ahmed, et al.
Publicado: (2018)

Cardioprotective effect of metformin against doxorubicin cardiotoxicity in rats
por: Argun, Mustafa, et al.
Publicado: (2016)

Cardioprotective effect of metformin against doxorubicin cardiotoxicity in rats
por: Tseng, Yi-Tang
Publicado: (2016)

Review on the Role of Epigenetic Modifications in Doxorubicin-Induced Cardiotoxicity
por: Kumari, Himani, et al.
Publicado: (2020)

Regulated cell death pathways in doxorubicin-induced cardiotoxicity
por: Christidi, Effimia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0auq3l0g5dgr90ub61l27263js