Acute lymphoblastic leukemia-derived extracellular vesicles affect quiescence of hematopoietic stem and progenitor cells

Patient-derived xenografted (PDX) models were generated through the transplantation of primary acute lymphoblastic leukemia (ALL) cells into immunodeficient NSG mice. We observed that ALL cells from mouse bone marrow (BM) produced extracellular vesicles (EVs) with specific expression of inducible he...

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Detalles Bibliográficos
Autores principales: Georgievski, Aleksandra, Michel, Anaïs, Thomas, Charles, Mlamla, Zandile, Pais de Barros, Jean-Paul, Lemaire-Ewing, Stéphanie, Garrido, Carmen, Quéré, Ronan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005650/
https://www.ncbi.nlm.nih.gov/pubmed/35414137
http://dx.doi.org/10.1038/s41419-022-04761-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005650/
https://www.ncbi.nlm.nih.gov/pubmed/35414137
http://dx.doi.org/10.1038/s41419-022-04761-5

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