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LSD1 is required for euchromatic origin firing and replication timing

The chromatin-based rule governing the selection and activation of replication origins remains to be elucidated. It is believed that DNA replication initiates from open chromatin domains; thus, replication origins reside in open and active chromatin. However, we report here that lysine-specific deme...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Huang, Yunchao, Cheng, Edith, Liu, Xinhua, Zhang, Yu, Yang, Jianguo, Young, Jordan T. F., Brown, Grant W., Yang, Xiaohan, Shang, Yongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005705/
https://www.ncbi.nlm.nih.gov/pubmed/35414135
http://dx.doi.org/10.1038/s41392-022-00927-x