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Laminin matrix regulates beta-cell FGFR5 expression to enhance glucose-stimulated metabolism

We previously showed that pancreatic beta-cells plated on laminin matrix express reduced levels of FGFR1, a receptor linked to beta-cell metabolism and differentiation. Due to recent evidence that adult beta-cells also express FGFR5, a co-receptor for FGFR1, we now aim to determine the effect of lam...

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Detalles Bibliográficos
Autores principales: Pal, Vidhant, Wang, Yufeng, Regeenes, Romario, Kilkenny, Dawn M., Rocheleau, Jonathan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005713/
https://www.ncbi.nlm.nih.gov/pubmed/35414066
http://dx.doi.org/10.1038/s41598-022-09804-7