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Laminin matrix regulates beta-cell FGFR5 expression to enhance glucose-stimulated metabolism
We previously showed that pancreatic beta-cells plated on laminin matrix express reduced levels of FGFR1, a receptor linked to beta-cell metabolism and differentiation. Due to recent evidence that adult beta-cells also express FGFR5, a co-receptor for FGFR1, we now aim to determine the effect of lam...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005713/ https://www.ncbi.nlm.nih.gov/pubmed/35414066 http://dx.doi.org/10.1038/s41598-022-09804-7 |