Identification of a novel mechanism for reversal of doxorubicin-induced chemotherapy resistance by TXNIP in triple-negative breast cancer via promoting reactive oxygen-mediated DNA damage

Given that triple-negative breast cancer (TNBC) lacks specific receptors (estrogen and progesterone receptors and human epidermal growth factor receptor 2) and cannot be treated with endocrine therapy, chemotherapy has remained the mainstay of treatment. Drug resistance is reportedly the main obstac...

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Detalles Bibliográficos
Autores principales: Chen, Yiting, Feng, Xueping, Yuan, Yuhao, Jiang, Jiahui, Zhang, Peihe, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005717/
https://www.ncbi.nlm.nih.gov/pubmed/35414060
http://dx.doi.org/10.1038/s41419-022-04783-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005717/
https://www.ncbi.nlm.nih.gov/pubmed/35414060
http://dx.doi.org/10.1038/s41419-022-04783-z

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