Non-destructive crystallinity assessment of indomethacin in tablets made from smartFilms(®) using terahertz time-domain spectroscopy

We use terahertz (THz) time-domain spectroscopy (TDS) to assess the crystalline state of indomethacin (IM) when loaded in smartFilms®. We found that smartFilms favour the amorphous IM (A-IM) for low loading concentrations. For higher concentrations, IM recrystallizes in its [Formula: see text] - cry...

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Detalles Bibliográficos
Autores principales: Ornik, Jan, Heidrich, Lara, Schesny, Robert, Castro-Camus, Enrique, Keck, Cornelia M., Koch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005722/
https://www.ncbi.nlm.nih.gov/pubmed/35414681
http://dx.doi.org/10.1038/s41598-022-10041-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005722/
https://www.ncbi.nlm.nih.gov/pubmed/35414681
http://dx.doi.org/10.1038/s41598-022-10041-1

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