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Non-destructive crystallinity assessment of indomethacin in tablets made from smartFilms(®) using terahertz time-domain spectroscopy

We use terahertz (THz) time-domain spectroscopy (TDS) to assess the crystalline state of indomethacin (IM) when loaded in smartFilms®. We found that smartFilms favour the amorphous IM (A-IM) for low loading concentrations. For higher concentrations, IM recrystallizes in its [Formula: see text] - cry...

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Detalles Bibliográficos
Autores principales:	Ornik, Jan, Heidrich, Lara, Schesny, Robert, Castro-Camus, Enrique, Keck, Cornelia M., Koch, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005722/ https://www.ncbi.nlm.nih.gov/pubmed/35414681 http://dx.doi.org/10.1038/s41598-022-10041-1

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