Structural Identification of Individual Helical Amyloid Filaments by Integration of Cryo-Electron Microscopy-Derived Maps in Comparative Morphometric Atomic Force Microscopy Image Analysis

The presence of amyloid fibrils is a hallmark of more than 50 human disorders, including neurodegenerative diseases and systemic amyloidoses. A key unresolved challenge in understanding the involvement of amyloid in disease is to explain the relationship between individual structural polymorphs of a...

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Detalles Bibliográficos
Autores principales: Lutter, Liisa, Al-Hilaly, Youssra K., Serpell, Christopher J., Tuite, Mick F., Wischik, Claude M., Serpell, Louise C., Xue, Wei-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005780/
https://www.ncbi.nlm.nih.gov/pubmed/35077765
http://dx.doi.org/10.1016/j.jmb.2022.167466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005780/
https://www.ncbi.nlm.nih.gov/pubmed/35077765
http://dx.doi.org/10.1016/j.jmb.2022.167466

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