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Breast Density and Estradiol Are Major Determinants for Soluble TNF-TNF-R Proteins in vivo in Human Breast Tissue

High mammographic density and exposure to sex steroids are independent risk factors for breast cancer by yet unknown mechanisms. Inflammation is one hallmark of cancer and the tumor necrosis factor family of proteins (TNFSFs) and receptors (TNFRSFs) are key determinants of tissue inflammation. The r...

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Detalles Bibliográficos
Autores principales: Ekstrand, Jimmy, Zemmler, Maja, Abrahamsson, Annelie, Lundberg, Peter, Forsgren, Mikael, Dabrosin, Charlotta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005790/
https://www.ncbi.nlm.nih.gov/pubmed/35432372
http://dx.doi.org/10.3389/fimmu.2022.850240