GPR105-Targeted Therapy Promotes Gout Resolution as a Switch Between NETosis and Apoptosis of Neutrophils

The fate of infiltrating neutrophils in inflamed joints determines the development of acute gouty arthritis (AGA). GPR105 highly expressed in human neutrophils is sensitive to monosodium urate crystals (MSU); nevertheless, the roles of GPR105 in AGA remain unclear. Here, we show that GPR105 is signi...

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Detalles Bibliográficos
Autores principales: Liu, Chunxiao, Zhou, Mengze, Jiang, Wenjiao, Ye, Shumin, Tian, Sheng, Jiang, Cheng, Hao, Kun, Li, Huanqiu, Hu, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005804/
https://www.ncbi.nlm.nih.gov/pubmed/35432308
http://dx.doi.org/10.3389/fimmu.2022.870183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005804/
https://www.ncbi.nlm.nih.gov/pubmed/35432308
http://dx.doi.org/10.3389/fimmu.2022.870183

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