Expected Value of Sample Information to Guide the Design of Group Sequential Clinical Trials

INTRODUCTION: Adaptive designs allow changes to an ongoing trial based on prespecified early examinations of accrued data. Opportunities are potentially being missed to incorporate health economic considerations into the design of these studies. METHODS: We describe how to estimate the expected valu...

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Detalles Bibliográficos
Autores principales: Flight, Laura, Julious, Steven, Brennan, Alan, Todd, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005835/
https://www.ncbi.nlm.nih.gov/pubmed/34859693
http://dx.doi.org/10.1177/0272989X211045036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005835/
https://www.ncbi.nlm.nih.gov/pubmed/34859693
http://dx.doi.org/10.1177/0272989X211045036

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