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Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells

Skeletal muscle stem cells (MuSCs), also called satellite cells, are instrumental for postnatal muscle growth and skeletal muscle regeneration. Numerous signaling cascades regulate the fate of MuSCs during muscle regeneration but the molecular mechanism by which MuSCs sense mechanical stimuli remain...

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Detalles Bibliográficos
Autores principales: Peng, Yundong, Du, Jingjing, Günther, Stefan, Guo, Xinyue, Wang, Shengpeng, Schneider, Andre, Zhu, Li, Braun, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005960/
https://www.ncbi.nlm.nih.gov/pubmed/35395625
http://dx.doi.org/10.1016/j.redox.2022.102309