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The aldehyde hypothesis: metabolic intermediates as antimicrobial effectors

There are many reactive intermediates found in metabolic pathways. Could these potentially toxic molecules be exploited for an organism's benefit? We propose that during certain microbial infections, the production of inherently reactive aldehydes by an infected host is a previously unappreciat...

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Detalles Bibliográficos
Autores principales: Darwin, K. Heran, Stanley, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006002/
https://www.ncbi.nlm.nih.gov/pubmed/35414258
http://dx.doi.org/10.1098/rsob.220010