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From Qualitative to Quantitative AOP: A Case Study of Neurodegeneration

Adverse outcome pathways (AOPs) include a sequence of events that connect a molecular-level initiating event with an adverse outcome at the cellular level for human health endpoints, or at the population level for ecological endpoints. When there is enough quantitative understanding of the relations...

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Detalles Bibliográficos
Autores principales: Sinitsyn, Dennis, Garcia-Reyero, Natàlia, Watanabe, Karen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006165/
https://www.ncbi.nlm.nih.gov/pubmed/35434701
http://dx.doi.org/10.3389/ftox.2022.838729