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Characterization of extramedullary disease in B-ALL and response to CAR T-cell therapy

Chimeric antigen receptor (CAR) T cells effectively eradicate medullary B-cell acute lymphoblastic leukemia (B-ALL) and can traffic to and clear central nervous system (CNS) involvement. CAR T-cell activity in non-CNS extramedullary disease (EMD) has not been well characterized. We systematically ev...

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Detalles Bibliográficos
Autores principales: Holland, Elizabeth M., Yates, Bonnie, Ling, Alex, Yuan, Constance M., Wang, Hao-Wei, Stetler-Stevenson, Maryalice, LaLoggia, Michael, Molina, John C., Lichtenstein, Daniel A., Lee, Daniel W., Ligon, John A., Shalabi, Haneen, Ahlman, Mark A., Shah, Nirali N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006258/
https://www.ncbi.nlm.nih.gov/pubmed/34920453
http://dx.doi.org/10.1182/bloodadvances.2021006035