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CombiFlow: combinatorial AML-specific plasma membrane expression profiles allow longitudinal tracking of clones

Acute myeloid leukemia (AML) often presents as an oligoclonal disease whereby multiple genetically distinct subclones can coexist within patients. Differences in signaling and drug sensitivity of such subclones complicate treatment and warrant tools to identify them and track disease progression. We...

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Detalles Bibliográficos
Autores principales: Houtsma, Roos, van der Meer, Nisha K., Meijer, Kees, Morsink, Linde M., Hogeling, Shanna M., Woolthuis, Carolien M., Ammatuna, Emanuele, Nijk, Marije T., de Boer, Bauke, Huls, Gerwin, Mulder, André B., Schuringa, Jan Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006304/
https://www.ncbi.nlm.nih.gov/pubmed/34543390
http://dx.doi.org/10.1182/bloodadvances.2021005018