Triple combination of BET plus PI3K and NF-κB inhibitors exhibit synergistic activity in adult T-cell leukemia/lymphoma

Adult T-cell leukemia/lymphoma (ATL) is an aggressive T-cell lymphoproliferative malignancy caused by human T-cell leukemia virus type 1 (HTLV-1). ATL is an orphan disease with no curative drug treatment regimens urgently needing new combination therapy. HTLV-1-infected cells rely on viral proteins,...

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Detalles Bibliográficos
Autores principales: Daenthanasanmak, Anusara, Bamford, Richard N., Yoshioka, Makoto, Yang, Shyh-Ming, Homan, Philip, Karim, Baktiar, Bryant, Bonita R., Petrus, Michael N., Thomas, Craig J., Green, Patrick L., Miljkovic, Milos D., Conlon, Kevin C., Waldmann, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006306/
https://www.ncbi.nlm.nih.gov/pubmed/35030628
http://dx.doi.org/10.1182/bloodadvances.2021005948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006306/
https://www.ncbi.nlm.nih.gov/pubmed/35030628
http://dx.doi.org/10.1182/bloodadvances.2021005948

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