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Single nucleotide polymorphism rs 2070874 at Interleukin-4 is associated with increased risk of type 1 diabetes mellitus independently of human leukocyte antigens

INTRODUCTION: Type 1 diabetes mellitus (T1DM) is characterized by autoimmune destruction of insulin-producing pancreatic beta (β-) cells. Previous studies suggested an imbalance between and pro- and anti-inflammatory cytokines exacerbates T1DM development. OBJECTIVES: We aimed to test the hypothesis...

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Detalles Bibliográficos
Autores principales: Osman, Awad E, Brema, Imad, AlQurashi, Alaa, Al-Jurayyan, Abdullah, Bradley, Benjamin, Hamza, Muaawia A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006359/
https://www.ncbi.nlm.nih.gov/pubmed/35404688
http://dx.doi.org/10.1177/03946320221090330