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A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype

BACKGROUND: Asthma is a heterogeneous disease; therefore, biomarkers that can assist in the identification of subtypes and direct therapy are highly desirable. Asthma is a chronic inflammatory disease that leads to changes in the extracellular matrix (ECM) by matrix metalloproteinases (MMPs) degrada...

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Detalles Bibliográficos
Autores principales: Rønnow, Sarah Rank, Sand, Jannie Marie Bülow, Staunstrup, Line Mærsk, Bahmer, Thomas, Wegmann, Michael, Lunding, Lars, Burgess, Janette, Rabe, Klaus, Sorensen, Grith Lykke, Fuchs, Oliver, Mutius, Erika V., Hansen, Gesine, Kopp, Matthias Volkmar, Karsdal, Morten, Leeming, Diana Julie, Weckmann, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006548/
https://www.ncbi.nlm.nih.gov/pubmed/35418159
http://dx.doi.org/10.1186/s40733-022-00084-6